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May combat cytokine release syndrome and pulmonary symptoms in severely ill COVID-19 patients. Interim results from the Solidarity trial suggest that IFN beta-1a has little or no effect on mortality in patients who are hospitalised with COVID-19 . Preliminary results from the RECOVERY trial suggest that dexamethasone reduced deaths by 35% in ventilated patients and by 20% in other patients receiving oxygen only. There was no benefit among those patients who did not require respiratory support . Pre-clinical and clinical data have shown molnupiravir to be active against the most common SARS-CoV-2 variants. |
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